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Yfr2 (cYanobacterial functional RNA-2 later published as Cyano-1 RNA motif)〔 is a family of non-coding RNAs. Members of the Yrf2 family have been identified in almost all studied species of cyanobacteria. The family was identified through a bioinformatics screen of published cyanobacterial genomes, having previously been grouped in a family of Yfr2-5.〔 The cyano-1 RNA motif family is essentially a synonym for Yfr2, although Cyano-1 does not include the terminator sequence and Yfr2 does.〔〔 The function of this ncRNA is unknown,〔〔 though it has been hypothesised that family members interact with RNA targets through kissing complexes using their highly conserved exposed central consensus element (CSE: IUPAC 5'-RKT SGA AAC WHG GHM ASA M-3').〔 Earlier studies noted a similarity to quorum sensing ncRNAs in ''Vibrio'' bacteria. The family can be divided into two subgroups, one found in marine cyanobacteria (e.g. the ''Prochlorococcus'' and ''Synechococcus'' genera) and the other from freshwater cyanobacteria. Both subgroups have lengths of 63-100 nucleotides (with the marine subgroup genes being on average 22nt longer),〔 a conserved 5' region and the characteristic Yfr2 CSE. Their secondary structures differ, however, with Yfr2 from marine picocyanobacteria having an additional stem loop.〔 The position of Yfr2 genes is generally unconserved,〔 but yfr2a orthologs were identified as being located 3' to the gene 50s ribosomal subunit gene (rplL ) in almost all marine cyanobacteria studied.〔 In the ''Prochlorococcus'' genus, Yfr2 genes are found adjacent to Yfr10 and a potential interaction between the two ncRNAs has been theorised. The initial bioinformatics scan which identified yfr2 also identified yfr1, a functional RNA which is upregulated during stress conditions.〔 Yfr families have now been identified up to yfr21.〔 ==See also== * Non-coding RNA * Yfr1 * Cyano-2 RNA motif * Cyano-S1 RNA motif 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Yfr2」の詳細全文を読む スポンサード リンク
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